Dr Rudy Sinharay

Background

Dr Rudy Sinharay is a consultant respiratory physician who specialises in the management of a broad range of respiratory conditions. He has a particular interest in lung cancer screening, and is the lead clinician for the lung cancer service at St Mary’s Hospital, Imperial College Healthcare NHS Trust.

His clinical expertise includes lung cancer, cough, asthma, COPD, pleural diseases, and breathlessness. He is highly experienced in performing advanced diagnostic procedures such as bronchoscopy, endobronchial ultrasound (EBUS), and various pleural interventions.

He completed his specialist training in respiratory and general internal medicine in London, gaining extensive experience at major teaching hospitals such as St Bartholomew’s Hospital, Royal Free Hospital, and University College London Hospital. Before taking on a consultant role at St Mary’s Hospital, Imperial College Healthcare Trust in 2019, Dr. Sinharay worked as a consultant at Guy’s and St Thomas’ NHS Foundation Trust.

Dr Sinharay holds an MD(res) from Imperial College London for his research conducted at the Royal Brompton Hospital, which explored the impact of air pollution on patients with chronic obstructive pulmonary disease (COPD) and ischaemic heart disease. He continues to contribute to academia as an Honorary Clinical Senior Lecturer at the National Heart and Lung Institute, Imperial College London.

Dr Sinharay’s 20 years' experience as a doctor dedicated to patient care, combined with his academic contributions and procedural expertise, ensures comprehensive and high-quality care for his patients.

Expertise

Asthma, breathlessness, bronchoscopy, cough, COPD, EBUS, lung cancer, lung nodules, pleural disorders, respiratory conditions, respiratory infections.

Research & publications

Dr. Sinharay holds an MD(res) from Imperial College London for his research conducted at the Royal Brompton Hospital, which explored the impact of air pollution on patients with chronic obstructive pulmonary disease (COPD) and ischaemic heart disease. He continues to contribute to academia as an Honorary Clinical Senior Lecturer at the National Heart and Lung Institute, Imperial College London.

Journal article

 Secondary spontaneous pneumothorax as the presenting manifestation of filamin A-associated lung disease.
Holden S, Barker AP, Babar J, Karia S, Gupta N, Sinharay R, Marciniak SJ. ERJ Open Res. 2024 Sep 30;10(5):00011-2024. doi: 10.1183/23120541.00011-2024. eCollection 2024 Sep. PMID: 39351381

Journal article

Multiomic Signatures of Traffic-Related Air Pollution in London Reveal Potential Short-Term Perturbations in Gut Microbiome-Related Pathways.
Cheng SL, Hedges M, Keski-Rahkonen P, Chatziioannou AC, Scalbert A, Chung KF, Sinharay R, Green DC, de Kok TMCM, Vlaanderen J, Kyrtopoulos SA, Kelly F, Portengen L, Vineis P, Vermeulen RCH, Chadeau-Hyam M, Dagnino S. Environ Sci Technol. 2024 May 21;58(20):8771-8782. doi: 10.1021/acs.est.3c09148. Epub 2024 May 10. PMID: 38728551

Journal article

Relationship between free and total malondialdehyde, a well-established marker of oxidative stress, in various types of human biospecimens
9 May 2018 JOURNAL OF THORACIC DISEASE 10(5):3088-+ (11 pages)AME PUBL CO
Cui X, Gong J, Han H, He L, Teng Y, Tetley T, Sinharay R, Chung KF, Islam T, Gilliland F, Grady S, Garshick E, Li Z, Zhang JJ
DOI: 10.21037/jtd.2018.05.92

Journal article

The human circulating miRNome reflects multiple organ disease risks in association with short-term exposure to traffic-related air pollution
Apr 2018 Environment International 113:26-34Elsevier
Krauskopf J, Caiment F, van Veldhoven K, Chadeau-Hyam M, Sinharay R, Chung KF, Cullinan P, Collins P, de Kok TM, Kelly F, Vermeulen R, Vineis P, Kleinjans JC
DOI: 10.1016/j.envint.2018.01.014

Journal article

Respiratory and cardiovascular responses to walking down a traffic-polluted road compared with walking in a traffic-free area in participants older than 60 years with chronic lung or heart disease and age-matched healthy controls: a randomised, crossover study (vol 391, pg 339, 2017)
27 Jan 2018 LANCET 391(10118):308 (1 page)ELSEVIER SCIENCE INC
Rudy Sinharay, Jicheng Gong, Benjamin Barratt, Pamela Ohman-Strickland, Sabine Ernst, Prof Frank J Kelly, Prof Junfeng (Jim) Zhang, Prof Peter Collins, Prof Paul Cullinan, Prof Kian Fan Chung

Journal article

Cys34 Adductomes Differ between Patients with Chronic Lung or Heart Disease and Healthy Controls in Central London
19 Jan 2018 Environmental Science and Technology (Washington)52(4):2307-2313American Chemical Society
Co-authors: Liu S, Grigoryan H, Edmands WMB, Dagnino S, Sinharay R, Cullinan P, Collins P, Chung KF, Barratt B, Kelly F, Vineis P, Rappaport SM
DOI: 10.1021/acs.est.7b05554

Conference

EGFR mutation specific immunohistochemistry revolutionises time to treatment with tyrosine kinase inhibitors (TKIs)
Jan 2018 LUNG CANCER 115:S24 (1 page) ELSEVIER IRELAND LTD
Sinharay R, Mithra S, Patel P, Ah-Moye A, Morrow S, Khiroya R, Falzon M, Borg E, Ahmed T, Forster M, Navani N
DOI: 10.1016/S0169-5002(18)30085-0

Journal article

Sputum-to-serum hydrogen sulfide ratio in COPD
Oct 2014 THORAX 69(10):903-909 (7 pages)BMJ PUBLISHING GROUP
Saito J, Mackay AJ, Rossios C, Gibeon D, Macedo P, Sinharay R, Bhavsar PK, Wedzicha JA, Chung KF
DOI: 10.1136/thoraxjnl-2013-204868